abstract：BACKGROUND:A cyclodialysis cleft often leads to direct communication between the anterior chamber and the suprachoroidal space. It is a rare condition that is encountered with blunt trauma, and less commonly, after surgery. Hypotony is the major sequelae that may lead to hypotonous maculopathy, optic disc edema, cornea...

journal_title：BMC ophthalmology

authors： Bair H,Lin CJ,Lai CT,Hsia NY,Tsai YY

更新日期：2020-03-23 00:00:00

abstract：BACKGROUND:Classification of optical coherence tomography (OCT) images can be achieved with high accuracy using classical convolution neural networks (CNN), a commonly used deep learning network for computer-aided diagnosis. Classical CNN has often been criticized for suppressing positional relations in a pooling layer...

journal_title：BMC ophthalmology

authors： Tsuji T,Hirose Y,Fujimori K,Hirose T,Oyama A,Saikawa Y,Mimura T,Shiraishi K,Kobayashi T,Mizota A,Kotoku J

更新日期：2020-03-19 00:00:00

abstract：BACKGROUND:To evaluate the differences between the predicted and achieved lenticule thickness (ΔLT) after small incision lenticule extraction (SMILE) surgery and investigate relationships between ΔLT and predicted lenticule thickness in SMILE. METHODS:A total of 184 eyes from 184 consecutive patients who underwent SMI...

journal_title：BMC ophthalmology

authors： Wu F,Yin H,Chen X,Yang Y

更新日期：2020-03-17 00:00:00

abstract：BACKGROUND:Retinoblastoma (RB) is the most frequent pediatric retinal tumor. In the present study, to elucidate chemoresistance mechanisms and identify potential biomarkers in RB, we utilized RNA sequencing (RNAseq) technological platforms to reveal transcriptome profiles and identify any differentially expressed genes...

journal_title：BMC ophthalmology

authors： Song WP,Zheng S,Yao HJ,Zhou XF,Li R,Zhang CY,Zhao JY,Wang LW,Shao RG,Li L

更新日期：2020-03-06 00:00:00

abstract：BACKGROUND:The current study compared optical quality before and after implantation of a posterior chamber phakic intraocular lens with a central hole [V4c implantable collamer lens (ICL)] under bright and dark lighting conditions by means of the Optical Quality Analysis System™ (OQAS; Visiometrics, Terrassa, Spain). ...

journal_title：BMC ophthalmology

authors： He T,Zhu Y,Zhou J

更新日期：2020-03-04 00:00:00

abstract：BACKGROUND:Cataract surgery in diabetics is more technically challenging due to a number of factors including poor intraoperative pupil dilation and a higher risk of vision threatening complications. This study evaluates the safety and efficacy of an intracameral combination of 2 mydriatics and 1 anesthetic (ICMA, Mydr...

journal_title：BMC ophthalmology

authors： Labetoulle M,Behndig A,Tassignon MJ,Nuijts R,Mencucci R,Güell JL,Pleyer U,Szaflik J,Rosen P,Bérard A,Chiambaretta F,Cochener-Lamard B,Intracameral Mydrane (ICMA), Ethics Group.

更新日期：2020-03-03 00:00:00

abstract：BACKGROUND:The primary aim was to estimate the incidence of primary and secondary childhood glaucoma in Scotland over a 2-year period. The secondary aim was to gauge the confidence and experience of ophthalmologists in Scotland in managing these patients. METHODS:A 7 question electronic survey was distributed to all c...

journal_title：BMC ophthalmology

authors： Beck D,Galea M,Loo CY,Schmoll C,Burgess FR,Montgomery D,Tatham AJ

更新日期：2020-02-27 00:00:00

abstract：BACKGROUND:Retinitis pigmentosa (RP) is a kind of inherited retinal degenerative diseases characterized by the progressive loss of photoreceptors. RP has been a conundrum without satisfactory countermeasures in clinic until now. Acetaldehyde dehydrogenase 2 (ALDH2), a major enzyme involved in aldehyde detoxification, h...

journal_title：BMC ophthalmology

authors： Yan W,Long P,Wei D,Yan W,Zheng X,Chen G,Wang J,Zhang Z,Chen T,Chen M

更新日期：2020-02-18 00:00:00

abstract：BACKGROUND:Older drivers have a crash rate nearly equal to that of young drivers whose crash rate is the highest among all age groups. Contrast sensitivity impairment is common in older adults. The purpose of this study is to examine whether parameters from the photopic and mesopic contrast sensitivity functions (CSF) ...

journal_title：BMC ophthalmology

authors： Owsley C,Swain T,Liu R,McGwin G Jr,Kwon MY

更新日期：2020-02-04 00:00:00

abstract：BACKGROUND:The case describes a rare entity. Most cases of IOL dislocation are associated with surgical trauma or preexisting zonulopathy. This patient presents IOL dislocation following routine exam, suggesting the need of careful evaluation of zonular integrity on pseudopahkic patients. METHODS:Patient is a 65 year ...

journal_title：BMC ophthalmology

authors： Castanos MV,Najac T,Dauhajre J,Buxton DF

更新日期：2020-01-30 00:00:00

abstract：BACKGROUND:To study the therapeutic effect of bone marrow-derived mesenchymal stem cells (BMSC) against retinal neovascularization and to compare with anti-vascular endothelial growth factor (VEGF) therapy. METHODS:Neonatal C57BL/6 mice were exposed in hyperoxygen and returned to room air to develop oxygen-induced ret...

journal_title：BMC ophthalmology

authors： Xu W,Cheng W,Cui X,Xu G

更新日期：2020-01-06 00:00:00

abstract：BACKGROUND:To study the influencing factors for different healing patterns of patients with idiopathic macular holes (IMH) after vitrectomy surgery performed with the internal limiting membrane (ILM) flap technique. METHODS:This study was a retrospective, consecutive, observational case series study. We recruited 52 I...

journal_title：BMC ophthalmology

authors： Liu Y,Wu C,Wang Y,Dong Y,Liang D,Xiao B,Han Q,Chu Y

更新日期：2019-12-21 00:00:00

abstract：BACKGROUND:Epidemic keratoconjunctivitis (EKC) is one of the most common eye infections worldwide. The analysis of clinical manifestations in different age groups help better know the disease. This study aims to provide more detailed analysis of 272 cases of EKC in 8 years, describe the differences of the clinical feat...

journal_title：BMC ophthalmology

authors： Hou W,Sun X,Feng J,Zhang Y,Wang Z

更新日期：2019-12-19 00:00:00

abstract：BACKGROUND:Uncorrected refractive errors contribute enormously to the burden of avoidable visual impairment worldwide. There is a huge disparity in different parts of the globe in context to spectacle coverage for distance vision. This study was undertaken with objectives of determining prevalence of spectacle coverage...

journal_title：BMC ophthalmology

authors： Malhotra S,Kalaivani M,Rath R,Prasad M,Vashist P,Gupta N,Senjam SS,Gupta SK

更新日期：2019-12-12 00:00:00

abstract：BACKGROUND:To determine the accuracy of the T2 formula as applied to highly myopic eyes, to compare the T2 formula to the SRK/T and Holladay 1 formulas, and to describe possible ways to improve the estimation of corneal height and prediction error in two settings, the Hadassah Hospital, Ophthalmology Department, Jerusa...

journal_title：BMC ophthalmology

authors： Idrobo-Robalino CA,Santaella G,Gutiérrez ÁM

更新日期：2019-11-12 00:00:00

abstract：BACKGROUND:The signaling pathway of epithelial to mesenchymal transition (EMT) is regulated by c-Src kinase in many cells. The purpose of this study was to investigate the effects of c-Src kinase on EMT of human lens epithelial cells in vivo stimulated by different factors. METHODS:Human lens epithelial cells, HLE-B3,...

journal_title：BMC ophthalmology

authors： Li X,Wang F,Ren M,Du M,Zhou J

更新日期：2019-11-08 00:00:00

abstract：BACKGROUND:To report the successful treatment of ocular toxoplasmosis and present the use of multimodal imaging to describe the changes in ocular toxoplasmic lesions subsequent to treatment. CASE PRESENTATION:A 73-year-old female visited the clinic with decreased visual acuity in the left eye. Fundus examination showe...

journal_title：BMC ophthalmology

authors： Park JH,Lee SY,Lee EK

更新日期：2019-09-05 00:00:00

abstract：BACKGROUND:With the diabetes mellitus (DM) prevalence increasing annually, the human grading of retinal images to evaluate DR has posed a substantial burden worldwide. SmartEye is a recently developed fundus image processing and analysis system with lesion quantification function for DR screening. It is sensitive to th...

journal_title：BMC ophthalmology

authors： Xu Y,Wang Y,Liu B,Tang L,Lv L,Ke X,Ling S,Lu L,Zou H

更新日期：2019-08-14 00:00:00

abstract：BACKGROUND:In this analysis, we aimed to systematically compare the complications which were associated with femtosecond laser-assisted cataract surgery (FLACS) versus the conventional phacoemulsification surgery (CPE). METHODS:Commonly used search databases, specifically MEDLINE, Cochrane Central, EMBASE, and http://...

journal_title：BMC ophthalmology

authors： Wang J,Su F,Wang Y,Chen Y,Chen Q,Li F

更新日期：2019-08-09 00:00:00

abstract：BACKGROUND:A patient's health literacy is fundamental for navigating the health system and managing disease. This study aimed to compare the health literacy levels of patients with chronic retinal disease in Denmark. METHODS:This cross-sectional questionnaire study used the validated HLS-EU-Q16 questionnaire to determ...

journal_title：BMC ophthalmology

authors： Jandorf S,Krogh Nielsen M,Sørensen K,Sørensen TL

更新日期：2019-08-08 00:00:00

abstract：BACKGROUND:The present study sought to introduce clinical characteristics and stepwise surgical strategies of isolated complete cryptophthalmos, a rare, congenital ocular anomaly. CASE PRESENTATION:Retrospective, noncomparative, clinical study. Six patients with isolated complete cryptophthalmos were diagnosed at the ...

journal_title：BMC ophthalmology

authors： Liu Z,Xie B,Li Y,Ding J,Li D

更新日期：2019-07-31 00:00:00

abstract：PURPOSE:To investigate the dynamic changes of hyperreflective foci (HF) in diabetic macular edema (DME) patients during the intravitreal Conbercept treatment in China. METHODS:DME Patients receiving intravitreal Conbercept (IVC) injections during the year 2016-2017 were retrospectively investigated. Thirteen patients ...

journal_title：BMC ophthalmology

authors： Liu S,Wang D,Chen F,Zhang X

更新日期：2019-07-23 00:00:00

abstract：BACKGROUND:To report the first case of a cerebral arteriovenous malformation (AVM) with ocular symptoms and review the characteristics of this case and the main point of confusion for the diagnosis of such a case. CASE PRESENTATION:A 58-year-old woman presented to the ophthalmology clinic with 1 and a half years of ri...

journal_title：BMC ophthalmology

authors： Shen S,Liu X,Chen J,Yang C,Shi C,Zhou Q

更新日期：2019-07-12 00:00:00

abstract：BACKGROUND:Anterior chamber depth (ACD) is becoming a hot topic and plays an important role in correcting the refractive errors (REs) after cataract surgery. The aim of this study was to assess the ACD changes and their relationship with the REs after phacoemulsification and intraocular lens (IOL) implantation in patie...

journal_title：BMC ophthalmology

authors： Ning X,Yang Y,Yan H,Zhang J

更新日期：2019-06-25 00:00:00

abstract：BACKGROUND:To evaluate the retinal function before and soon after an intravitreal injection of an anti-vascular endothelial growth factor (anti-VEGF) agents. METHODS:Seventy-nine eyes of 79 patients that were treated by an intravitreal injection of an anti-VEGF agent for age-related macular degeneration (AMD), diabeti...

journal_title：BMC ophthalmology

authors： Terauchi G,Shinoda K,Sakai H,Kawashima M,Matsumoto CS,Mizota A,Miyake Y

更新日期：2019-06-17 00:00:00

abstract：BACKGROUND:To evaluate the prognosis of Chinese patients with lacrimal gland adenoid cystic carcinoma treated with eye-sparing surgery and adjuvant multimodal therapy. METHODS:The study included 24 consecutive patients with lacrimal gland adenoid cystic carcinoma treated at the Ninth People's Hospital of Shanghai from...

journal_title：BMC ophthalmology

authors： Yang J,Zhou C,Wang Y,Fan X,Jia R

更新日期：2019-06-08 00:00:00

abstract：BACKGROUND:To examine morphological and functional results after pars plana vitrectomy (PPV) with sulfur hexafluoride (SF6) gas tamponade due to macula-on and macula-off rhegmatogenous retinal detachment (RRD) during 6 months of the follow-up. METHODS:The study included 62 eyes that underwent successful PPV with SF6 t...

journal_title：BMC ophthalmology

authors： Borowicz D,Nowomiejska K,Nowakowska D,Brzozowska A,Toro MD,Avitabile T,Jünemann AG,Rejdak R

更新日期：2019-05-24 00:00:00

abstract：BACKGROUND:To present the follow-up outcomes of a modified technique of transscleral suture fixation of posterior chamber intraocular lens (PCIOL) in eyes with inadequate capsule support. METHODS:A retrospective chart review of 21 patients underwent transscleral suture fixation of a foldable 3-looped haptics one-piece...

journal_title：BMC ophthalmology

authors： Ni S,Wang W,Chen X,Wu X,He S,Ma Y,Xu W

更新日期：2019-05-09 00:00:00

abstract：BACKGROUND:To evaluate the effectiveness of intravitreal bevacizumab (IVB) and intravitreal ranibizumab (IVR) in actual practice for treating patients with retinal diseases in Thailand. METHODS:A prospective, multi-centre, observational study was conducted among eight hospitals in their ophthalmology outpatient depart...

journal_title：BMC ophthalmology

authors： Kumluang S,Ingsrisawang L,Sangroongruangsri S,Chaikledkaew U,Ratanapakorn T,Ruamviboonsuk P,Taweebanjongsin W,Choovuthayakorn J,Thoongsuwan S,Hanutsaha P,Kulvichit K,Ratanapojnard T,Wongsawad W,Leelahavarong P,Teerawattananon

更新日期：2019-03-29 00:00:00

abstract：BACKGROUND:Stress-induced activation of the sympathetic nervous system leads to a cascade of metabolic reactions. Emotional stress is a more specific form of stress in which the stressor is a psychological response to a situation subjectively perceived as traumatic. Stress hormones can have a wide range of effects on t...

journal_title：BMC ophthalmology

authors： Gillmann K,Hoskens K,Mansouri K

更新日期：2019-03-08 00:00:00

abstract：BACKGROUND:To evaluate the 6-month clinical outcomes of Flexivue Microlens refractive corneal inlay in emmetropic patients in Asia for the surgical compensation of presbyopia. METHODS:In this retrospective study, corneal inlay implantation was done using a femtosecond laser. The follow-up period was 6 months. Near/int...

journal_title：BMC ophthalmology

authors： Han G,Lim DH,Yang CM,Park GH,Park DY,Moon HS,Lee JM,Lee JH,Chung TY

更新日期：2019-03-05 00:00:00

abstract：BACKGROUND:Patients with primary angle closure/glaucoma (PAC/PACG) with extensive peripheral anterior synechiae (PAS), and coexisting cataract, increasingly have been treated with phacoemulsification combined with goniosynechialysis (Phaco-GSL). Since the mechanisms of acute and chronic PAC/PACG may differ, the treatme...

journal_title：BMC ophthalmology

authors： Tian T,Li M,Pan Y,Cai Y,Fang Y

更新日期：2019-03-04 00:00:00

abstract：BACKGROUND:To evaluate the efficacy, complications, and clinical characteristics, including the ocular toxicity, of intravitreal melphalan(IVM) treatment for vitreous seeding in Chinese retinoblastoma patients. METHODS:This was a retrospective, non-comparative analysis including 30 consecutive eyes of 23 patients with...

journal_title：BMC ophthalmology

authors： Xue K,Ren H,Meng F,Zhang R,Qian J

更新日期：2019-02-26 00:00:00

abstract：BACKGROUND:To evaluate the effects of anterior capsular opening size on deviation from predicted refraction and the effective position of the intraocular lens (ELP) in cataract surgery. METHODS:Nonrandomized clinical trial. Eighty patients (80 eyes) with simple age-related cataracts were treated from May 2018 to Septe...

journal_title：BMC ophthalmology

authors： Li S,Hu Y,Guo R,Shao Y,Zhao J,Zhang J,Wang J

更新日期：2019-02-21 00:00:00

abstract：BACKGROUND:To report a case of orbital inflammation after bisphosphonate infusion in a patient who was already receiving immunosuppressive therapy. CASE PRESENTATION:A 56-year-old woman presented to the ophthalmology clinic with acute onset of right eye pain 24 h after receiving her first Zolendronic acid infusion. Sh...

journal_title：BMC ophthalmology

authors： Herrera I,Kam Y,Whittaker TJ,Champion M,Ajlan RS

更新日期：2019-02-14 00:00:00

abstract：BACKGROUND:A few case reports have described accidental eye injuries caused by fish hooks. The severity of ocular injuries is dependent on the involved ocular structures. Severe ocular injuries due to fish hooks are rare. We describe open globe and penetrating eyelid injuries from fish hooks at the Baltic Sea. METHODS...

journal_title：BMC ophthalmology

authors： Purtskhvanidze K,Saeger M,Treumer F,Nölle B,Roider J

更新日期：2019-01-21 00:00:00

abstract：BACKGROUND:Diabetic macular edema (DME) can be treated with different alternatives, among them Dexamethasone intravitreal implant 0.7 mg (DEX 0.7) has demonstrated that may improve both central macular thickness (CMT) and best corrected visual acuity (BCVA). This study aimed to evaluate the effect of the intravitreal d...

journal_title：BMC ophthalmology

authors： Castro-Navarro V,Cervera-Taulet E,Navarro-Palop C,Monferrer-Adsuara C,Hernández-Bel L,Montero-Hernández J

更新日期：2019-01-11 00:00:00

abstract：BACKGROUND:Retinal vein occlusion (RVO) is a common retinal venous disorder that causes vision loss. No specific therapy has been developed. Controversy exists regarding two treatments: intravitreal dexamethasone implants and anti-vascular endothelial growth factor (VEGF). The goal of this study is to compare the effec...

journal_title：BMC ophthalmology

authors： Gao L,Zhou L,Tian C,Li N,Shao W,Peng X,Shi Q

更新日期：2019-01-08 00:00:00

abstract：BACKGROUND:To assess visual outcomes over 24 months in patients with neovascular age-related macular degeneration (nAMD) who initiated intravitreal aflibercept therapy under a treat-and-extend (TE) regimen in real-world settings. METHODS:In this retrospective, observational, multicentre study in Slovenia, medical reco...

journal_title：BMC ophthalmology

authors： Jaki Mekjavić P,Gregorčič B,Oberč C,Podgoršek S

更新日期：2018-12-20 00:00:00

abstract：BACKGROUND:The ability to image wide fundus fields and to conduct swift, non-invasive examinations is increasingly important with the escalation in patients with diabetic retinopathy (DR). METHODS:Fifty eyes of 28 consecutive patients with DR were examined in this prospective observational study. A total of 46 eyes, 2...

journal_title：BMC ophthalmology

authors： Hirano T,Imai A,Kasamatsu H,Kakihara S,Toriyama Y,Murata T

更新日期：2018-12-20 00:00:00